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MicroRNA-542-3p regulates P-glycoprotein expression in rat epilepsy via the toll-like receptor 4/Nuclear factor-kappa B signaling pathway.

08:00 EDT 23rd October 2019 | BioPortfolio

Summary of "MicroRNA-542-3p regulates P-glycoprotein expression in rat epilepsy via the toll-like receptor 4/Nuclear factor-kappa B signaling pathway."

Function of microRNA-542-3p (miR-542-3p) in rat epilepsy is still unclear.

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This article was published in the following journal.

Name: Current neurovascular research
ISSN: 1875-5739
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Medical and Biotech [MESH] Definitions

A pattern recognition receptor that forms heterodimers with TOLL-LIKE RECEPTOR 2.

A pattern recognition receptor that forms heterodimers with other TOLL-LIKE RECEPTORS. It interacts with multiple ligands including PEPTIDOGLYCAN, bacterial LIPOPROTEINS, lipoarabinomannan, and a variety of PORINS.

A family of pattern recognition receptors characterized by an extracellular leucine-rich domain and a cytoplasmic domain that share homology with the INTERLEUKIN 1 RECEPTOR and the DROSOPHILA toll protein. Following pathogen recognition, toll-like receptors recruit and activate a variety of SIGNAL TRANSDUCING ADAPTOR PROTEINS.

A DNA-binding orphan nuclear receptor that negatively regulates expression of ARNTL TRANSCRIPTION FACTORS and plays a role as a regulatory component of the circadian clock system. The Nr1d1 nuclear receptor expression is cyclically-regulated by a feedback loop involving its positive regulation by CLOCK PROTEIN; BMAL1 PROTEIN heterodimers and its negative regulation by CRYPTOCHROME and PERIOD PROTEINS.

A pattern recognition receptor that forms heterodimers with TLR2 RECEPTOR. The complex interacts with a variety of ligands including LIPOPROTEINS from MYCOPLASMA.

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