Molecular characterisation of a Marek's disease virus strain detected in tumour-bearing turkeys.

07:00 EST 8th November 2019 | BioPortfolio

Summary of "Molecular characterisation of a Marek's disease virus strain detected in tumour-bearing turkeys."

Marek's disease (MD) is a lymphoproliferative disease caused by (GaHV-2), which primarily affects chickens. However, the virus is also able to induce tumours in turkeys, albeit less frequently than in chickens. This study reports the molecular characterisation of a GaHV-2 strain detected in a flock of Italian meat-type turkeys exhibiting visceral lymphomas. Sequencing and phylogenetic analysis of the gene revealed that the turkey GaHV-2 has molecular features of high virulence and genetic similarity with GaHV-2 strains recently detected in Italian commercial and backyard chickens. GaHV-2 is ubiquitous among chickens despite the vaccination, and chicken-to-turkey transmission is hypothesised due to the presence of broilers in neighbouring pens. A GaHV-2 strain from Italian turkeys was molecularly characterised;The turkey strain presented molecular characteristics of high virulence in its gene;The turkey strain was closely related to previously detected chicken strains.


Journal Details

This article was published in the following journal.

Name: Avian pathology : journal of the W.V.P.A
ISSN: 1465-3338
Pages: 1-21


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