Association between Modic changes, disc degeneration, and neck pain in the cervical spine: a systematic review of literature.

07:00 EST 12th November 2019 | BioPortfolio

Summary of "Association between Modic changes, disc degeneration, and neck pain in the cervical spine: a systematic review of literature."

The contribution of Modic changes (MCs) in relation to spinal pain and degenerative changes has been evaluated frequently. However, most studies focus on lumbar spine. The association between MCs, neck pain and cervical disc degeneration is not clear.


Journal Details

This article was published in the following journal.

Name: The spine journal : official journal of the North American Spine Society
ISSN: 1878-1632


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The replacement of intervertebral discs in the spinal column with artificial devices. The procedure is done in the lumbar or cervical spine to relieve severe pain resulting from INTERVERTEBRAL DISC DEGENERATION.

Degenerative changes in the INTERVERTEBRAL DISC due to aging or structural damage, especially to the vertebral end-plates.

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Fibrocartilage inner core of the intervertebral disc. Prolapsed or bulged nucleus pulposus leads to INTERVERTEBRAL DISC DISPLACEMENT while proliferation of cells in the nucleus pulposus is associated with INTERVERTEBRAL DISC DEGENERATION.

The dissolving of the NUCLEUS PULPOSUS, the semi-gelatinous tissue of a displaced INTERVERTEBRAL DISC. It is usually achieved by the direct injection of a proteolytic enzyme, especially CHYMOPAPAIN, into the herniated disc.

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