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In pharmaceutical compounding, the term "primary engineering control" usually refers to a device used to reduce the number of airborne particles and microorganisms in the compounding suite by channeling filtered unidirectional high-efficiency particulate air into areas that must be as contaminant free as possible. In this article, which is the first in a 2-part series, several types of primary engineering controls (unidirectional-airflow workstations, compounding aseptic isolators, compounding aseptic containment isolators) used to achieve that goal are discussed, as is laminar airflow in those units and the use of casters and hydraulic lifts. In part 2, several classes of biosafety cabinets used for that purpose in compounding are examined.
This article was published in the following journal.
Name: International journal of pharmaceutical compounding
Minimizing contamination by airborne particulates is essential in pharmaceutical compounding, and biosafety cabinets have long been among the most effective types of equipment used to achieve that goa...
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Assessment of the Safety and Ability of a Once-a-day Dose of an Orally Inhaled Medicine [ie, Glycopyrrolate Inhalation Solution = GIS] to Improve Airflow in the Lungs When Delivered With an Electronic eFlow Nebulizer System in Patients With Chronic Obstru
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The aim of this study is to perform the bone tissue engineering to reconstruct the alveolar bone defect in cleft lip and palate patients using mesenchymal stem cells from deciduous dental ...
The physical or mechanical action of the LUNGS; DIAPHRAGM; RIBS; and CHEST WALL during respiration. It includes airflow, lung volume, neural and reflex controls, mechanoreceptors, breathing patterns, etc.
Hospital department whose primary function is the upkeep and supervision of the buildings and grounds and the maintenance of hospital physical plant and equipment which requires engineering expertise.
A non-aqueous co-solvent that serves as tool to study protein folding. It is also used in various pharmaceutical, chemical and engineering applications.
Change brought about to an organisms genetic composition by unidirectional transfer (TRANSFECTION; TRANSDUCTION, GENETIC; CONJUGATION, GENETIC, etc.) and incorporation of foreign DNA into prokaryotic or eukaryotic cells by recombination of part or all of that DNA into the cell's genome.
Methods and techniques used to modify or select cells and develop conditions for growing cells for biosynthetic production of molecules (METABOLIC ENGINEERING), for generation of tissue structures and organs in vitro (TISSUE ENGINEERING), or for other BIOENGINEERING research objectives.