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The role of desmin alterations in mechanical electrical feedback in heart failure.

07:00 EST 30th November 2019 | BioPortfolio

Summary of "The role of desmin alterations in mechanical electrical feedback in heart failure."

Mechanoelectric feedback (MEF) was related to malignant arrhythmias in heart failure (HF). Desmin is a cytoskeleton protein and could be involved in MEF as a mechanoelectrical transducer. In this study, we will discuss the role of desmin alterations in mechanical electrical feedback in heart failure and its mechanisms.

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This article was published in the following journal.

Name: Life sciences
ISSN: 1879-0631
Pages: 117119

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Medical and Biotech [MESH] Definitions

A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.

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Methods to induce and measure electrical activities at specific sites in the heart to diagnose and treat problems with the heart's electrical system.

Heart failure caused by abnormal myocardial relaxation during DIASTOLE leading to defective cardiac filling.

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