Rbm14 maintains the integrity of genomic DNA during early mouse embryogenesis via mediating alternative splicing.

07:00 EST 3rd December 2019 | BioPortfolio

Summary of "Rbm14 maintains the integrity of genomic DNA during early mouse embryogenesis via mediating alternative splicing."

In this study, we generated an Rbm14 knockout mouse model to explore its functions during early mouse embryogenesis.


Journal Details

This article was published in the following journal.

Name: Cell proliferation
ISSN: 1365-2184
Pages: e12724


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Medical and Biotech [MESH] Definitions

An office of the UNITED STATES PUBLIC HEALTH SERVICE organized in June 1992 to promote research integrity and investigate misconduct in research supported by the Public Health Service. It consolidates the Office of Scientific Integrity of the National Institutes of Health and the Office of Scientific Integrity Review in the Office of the Assistant Secretary for Health.

A GLYCOINOSITOL PHOSPHOLIPID MEMBRANE ANCHOR-containing ephrin with a high affinity for the EPHA3 RECEPTOR. Early in embryogenesis it is expressed at high levels in the MESENCEPHALON; SOMITES; branchial arches, and LIMB BUDS.

Contiguous large-scale (1000-400,000 basepairs) differences in the genomic DNA between individuals, due to SEQUENCE DELETION; SEQUENCE INSERTION; or SEQUENCE INVERSION.

A family of metalloproteases that are related to the DROSOPHILA protein tolloid, which is a gene product necessary for dorsal-ventral patterning in early Drosophila embryogenesis. Many members of the group may play a significant role in intercellular signaling.

The systematic study of annotated genomic information to global protein expression in order to determine the relationship between genomic sequences and both expressed proteins and predicted protein sequences.

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