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Latest developments in in-vivo imaging for Proton therapy.

07:00 EST 3rd December 2019 | BioPortfolio

Summary of "Latest developments in in-vivo imaging for Proton therapy."

Owing to the favorable physical and biological properties of swift ions in matter, their application to radiation therapy for highly selective cancer treatment is rapidly spreading worldwide. To date over 90 ion therapy facilities are operational, predominantly with proton beams, and about the same amount is under construction or planning.Over the last decades considerable developments have been achieved in accelerator technology, beam delivery and medical physics to enhance conformation of the dose delivery to complex shaped tumour volumes, with excellent sparing of surrounding normal tissue and critical organs. Nevertheless, full clinical exploitation of the ion beam advantages is still challenged, especially by uncertainties in the knowledge of the beam range in the actual patient anatomy during the fractionated course of treatment, thus calling for continued multidisciplinary research in this rapidly emerging field.This contribution will review latest developments aiming to image the patient with the same beam quality as for therapy prior to treatment, and to visualize the treatment delivery by exploiting irradiation induced physical emissions, with different level of maturity from proof-of-concept studies in phantoms and first studies up to clinical testing and initial clinical evaluation.

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This article was published in the following journal.

Name: The British journal of radiology
ISSN: 1748-880X
Pages: 20190787

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