Access to 2-Aroylthienothiazoles via C-H/N-O Bond Functionalization of Oximes.

07:00 EST 3rd December 2019 | BioPortfolio

Summary of "Access to 2-Aroylthienothiazoles via C-H/N-O Bond Functionalization of Oximes."

A novel strategy for the synthesis of 2-aroylthienothiazoles via C-H/N-O bond functionalization of ketoximes is developed. This reaction features excellent step- and atom-economy, as well as broad substrate scope. Various common ketoximes, even vinyl ketoximes, were efficiently converted to 2-aroylthienothiazoles. Preliminary mechanistic studies indicated that the radical process should be involved in this transformation. Moreover, the product exhibited good coordination with Cu(II), showing the potential application in the metal coordination field.


Journal Details

This article was published in the following journal.

Name: Organic letters
ISSN: 1523-7052


DeepDyve research library

PubMed Articles [4748 Associated PubMed Articles listed on BioPortfolio]

Multicomponent aromatic and benzylic Mannich reactions through C-H bond activation.

Multicomponent Mannich reactions through C-H bond activation is described. These transformations allowed the straightforward generation of densely substituted benzylic and homo-benzylic amines in good...

The photoredox alkylarylation of styrenes with alkyl N-hydroxyphthalimide esters and arenes involving C-H functionalization.

The In(OTf)3-promoted three-component photoredox alkylarylation of styrenes with alkyl NHP esters and arenes to access alkylated arene derivatives through C-C bond cleavage and C-H functionalization i...

Controllable α- or β-Functionalization of α-Diazoketones with Aromatic Amides via Cobalt-Catalyzed C-H Activation: A Regioselective Approach to Isoindolinones.

Efficient procedures for the selective α- or β-functionalization of α-diazoketones with aromatic amides were developed by using a cobalt catalyst under ligand-free conditions. Normal α-functionali...

Donor-Acceptor-Donor NIR II Emissive Rhodindolizine Dye Synthesized by C-H Bond Functionalization.

A NIR II emissive dye was synthesized by the C-H bond functionalization of 1-methyl-2-phenylindolizine with 3,6-dibromoxanthene. The rhodindolizine (RhIndz) spirolactone product was non-fluorescent; h...

Nucleophilic substitution: a facile strategy for selective B-H functionalization of carboranes.

Vertex-specific functionalization of carboranes has received considerable research interest, due to the valuable application of carborane derivatives in medicine, coordination/organometallic chemistry...

Clinical Trials [1969 Associated Clinical Trials listed on BioPortfolio]

Validation of Brief Objective Neurobehavioral Detectors (BOND) in Mild TBI

The Veterans Health Administration (VHA) has stated the need for a brief screening instrument that can assist with the triage of the enormous number of returning OEF/OIF veterans with conc...

Contribution of PRF in CDH in Children With Prothetic Patch Closure

Improved management of giant congenital diaphragmatic hernias (CDH) in neonates : decreased risk of morbidity and mortality due to prosthesis release. CDH is a rare disease with a still ve...

Clinical Evaluation of Three Dental Adhesive Systems in Class V Restorations

The purpose of this study is to compare the clinical performance of three dental adhesive systems used to bond Class V cavity fillings in adult teeth.

Impact of Premature Childbirth on Parental Outcomes During Baby's NICU Stay and Beyond

The main objective of this project is examining whether there is a relationship between preterm delivery and parental' problematic emotional bond in the early postpartum period. The secon...

Clinical Study Class II on Ceram.x Universal and Prime&Bond

Damage to teeth from decay or previous old silver fillings can be repaired with tooth-coloured filling materials that stick to the tooth. These materials have been around for some years an...

Medical and Biotech [MESH] Definitions

Compounds that contain the radical R2C=N.OH derived from condensation of ALDEHYDES or KETONES with HYDROXYLAMINE. Members of this group are CHOLINESTERASE REACTIVATORS.

An Act that amends Title XVIII of the Social Security Act to repeal the Medicare sustainable growth rate, that strengthens Medicare access by improving physician payments, and that reauthorizes the Children's Health Insurance Program (CHIP).

Agreement in which author(s) and copyright holder(s) grant(s) to all users a free, irrevocable, worldwide, perpetual right of access to, and a license to copy, use, distribute, transmit and display the work publicly and to make and distribute derivative works, in any digital medium for any responsible purpose, subject to proper attribution of authorship, as well as the right to make small numbers of printed copies for their personal use. A complete version of the work and all supplemental materials, including a copy of the permission as stated above, in a suitable standard electronic format is deposited immediately upon initial publication in at least one online repository that is supported by an academic institution, scholarly society, government agency, or other well-established organization that seeks to enable open access, unrestricted distribution, interoperability, and long-term archiving. (from Bethesda Statement on Open Access Publishing)

Derivatives of ERGOSTEROL formed by ULTRAVIOLET RAYS breaking of the C9-C10 bond. They differ from CHOLECALCIFEROL in having a double bond between C22 and C23 and a methyl group at C24.

Derivative of 7-dehydroxycholesterol formed by ULTRAVIOLET RAYS breaking of the C9-C10 bond. It differs from ERGOCALCIFEROL in having a single bond between C22 and C23 and lacking a methyl group at C24.

Quick Search

DeepDyve research library

Searches Linking to this Article