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Copper-Catalyzed Ring Opening of 1.1.1Propellane with Alkynes: Synthesis of Exocyclic Allenic Cyclobutanes.

07:00 EST 3rd December 2019 | BioPortfolio

Summary of "Copper-Catalyzed Ring Opening of 1.1.1Propellane with Alkynes: Synthesis of Exocyclic Allenic Cyclobutanes."

Despite the long history and interesting properties of propellanes, these compounds still have tremendous potential to be exploited in synthetic organic chemistry. Herein we disclose an experimentally simple procedure to achieve cyclobutane-containing allenes and alkynes through a copper-catalyzed ring opening of [1.1.1]propellane and subsequent reaction with ethynes.

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Name: Organic letters
ISSN: 1523-7052
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