Activity of native tick kinins and peptidomimetics on the cognate target G protein-coupled receptor from the cattle fever tick, Rhipicephalus microplus (Acari: Ixodidae).

07:00 EST 3rd December 2019 | BioPortfolio

Summary of "Activity of native tick kinins and peptidomimetics on the cognate target G protein-coupled receptor from the cattle fever tick, Rhipicephalus microplus (Acari: Ixodidae)."

Kinins are multifunctional neuropeptides that regulate key insect physiological processes such as diuresis, feeding, and ecdysis. However, the physiological roles of kinins in ticks are unclear. Further, ticks have an expanded number of kinin paracopies in the kinin gene. Silencing the kinin receptor in females of R. microplus reduces reproductive fitness. Thus, it appears the kinin signaling system is important for tick physiology, and its disruption may have potential for tick control.


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This article was published in the following journal.

Name: Pest management science
ISSN: 1526-4998


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