Rebuttal to Editorial: sodium retention by uPA in nephrotic syndrome?

07:00 EST 3rd December 2019 | BioPortfolio

Summary of "Rebuttal to Editorial: sodium retention by uPA in nephrotic syndrome?"

We welcome the opportunity to reply to the elegant editorial of Prof. Ehmke in which he highlights contradicting conclusions reached by Hinrichs et al. and by us in two recently published articles in Acta Physiologica. In our reply, we first comment on some technical aspects discussed by Prof. Ehmke as possible explanations for the discrepant conclusions reached in the two studies. In addition, we highlight some in vivo data reported by Hinrichs et al. which in our view do not oppose but rather support our conclusion that urokinase, also known as urokinase-type plasminogen activator (uPA), is not essential for sodium retention in nephrotic syndrome.


Journal Details

This article was published in the following journal.

Name: Acta physiologica (Oxford, England)
ISSN: 1748-1716
Pages: e13427


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