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Pharmacodynamic and pharmacokinetic profile of SM-1, a triple-drug combination to increase total sleep time.

07:00 EST 3rd December 2019 | BioPortfolio

Summary of "Pharmacodynamic and pharmacokinetic profile of SM-1, a triple-drug combination to increase total sleep time."

The primary objective was to characterize the pharmacokinetics and pharmacodynamics of SM-1 after administration of a single oral dose to healthy volunteers in a placebo-controlled double-blind trial of daytime sedation. Secondary objectives were to determine the onset, duration, and offset of the sedative effects using subjective and objective measures of sedation. Safety and tolerability of SM-1 were also investigated.

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This article was published in the following journal.

Name: Human psychopharmacology
ISSN: 1099-1077
Pages: e2716

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Inhibitor or Reverse Transcriptases or of RNA-dIrected DNA polymerase.

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