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Where do PBPK Models Stand in Pharmacometrics and Systems Pharmacology?

07:00 EST 6th January 2020 | BioPortfolio

Summary of "Where do PBPK Models Stand in Pharmacometrics and Systems Pharmacology?"

Modern population based Physiologically Based Pharmacokinetic models have contributed to the advancement of model informed drug development and regulatory decision-making. These models are developed based on principles of 'systems pharmacology', which covers a range of modeling approaches including 'Quantitative Systems Pharmacology'. To integrate pharmacometric and systems pharmacology approaches a profound understanding of the objectives and remits of each technique is required and new definitions, algorithms, model assessment criteria and tools are urgently needed.

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This article was published in the following journal.

Name: CPT: pharmacometrics & systems pharmacology
ISSN: 2163-8306
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