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A clinical analysis of 27 cases of simultaneous bilateral sudden sensorineural hearing loss.

07:00 EST 1st December 2019 | BioPortfolio

Summary of "A clinical analysis of 27 cases of simultaneous bilateral sudden sensorineural hearing loss."

To compare the clinical characteristics and therapeutic effects between simultaneous bilateral sudden sensorineural hearing loss(Si-BSSHL) and unilateral sudden sensorineural hearing loss(USSHL). The clinical data of 27 cases of Si-BSSHL were retrospectively analyzed, including the characteristics of the disease, clinical manifestations, audiological examination, hematological examination, and therapeutic effect, and compared with those of 139 cases of USSHL. There was a statistically significant difference in the age(65.85±9.17 vs 56.95±13.18, <0.01) and no significant difference in sex ratio(>0.05) between the two groups. The proportion of Si-BSSHL patients with vertigo, ear fullness, hypertension, diabetes, coronary heart disease and stroke had no statistical difference compared with those of USSHL(>0.05), the proportion of patients with tinnitus in Si-BSSHL group was significantly lower than that in USSHL group(<0.05). The distribution of hearing loss degree and the type of audiometry in Si-BSSHL group were significantly different from those in USSHL group, PTA before treatment and the proportion of profound hearing loss in Si-BSSHL group was significantly lower than that in USSHL group(<0.05), descending audiometry type was more common in Si-BSSHL group compared to USSHL(<0.01). Fibrinogen in Si-BSSHL group was significantly higher than that in USSHL group(<0.05). No significant difference was found between the two groups with respect to mean platelet volume, blood lipid and folic acid(>0.05). The total treatment effective rate in Si-BSSHL group was 44.44%, while that in USSHL group was 41.73%, there was no significant difference between the two groups(>0.05). Si-BSSHL has a female preponderance and tends to occur in advanced age in our cohort. Compared to USSHL patients, Si-BSSHL patients have less profound hearing loss and more descending audiograms, and the proportion of patients with extremely severe deafness is relatively small. There is no significant difference in the therapeutic effect between the two groups.

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This article was published in the following journal.

Name: Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery
ISSN: 1001-1781
Pages: 1134-1137

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Medical and Biotech [MESH] Definitions

Sensorineural hearing loss which develops suddenly over a period of hours or a few days. It varies in severity from mild to total deafness. Sudden deafness can be due to head trauma, vascular diseases, infections, or can appear without obvious cause or warning.

Hearing loss due to damage or impairment of both the conductive elements (HEARING LOSS, CONDUCTIVE) and the sensorineural elements (HEARING LOSS, SENSORINEURAL) of the ear.

Hearing loss resulting from damage to the COCHLEA and the sensorineural elements which lie internally beyond the oval and round windows. These elements include the AUDITORY NERVE and its connections in the BRAINSTEM.

Hearing loss due to disease of the AUDITORY PATHWAYS (in the CENTRAL NERVOUS SYSTEM) which originate in the COCHLEAR NUCLEI of the PONS and then ascend bilaterally to the MIDBRAIN, the THALAMUS, and then the AUDITORY CORTEX in the TEMPORAL LOBE. Bilateral lesions of the auditory pathways are usually required to cause central hearing loss. Cortical deafness refers to loss of hearing due to bilateral auditory cortex lesions. Unilateral BRAIN STEM lesions involving the cochlear nuclei may result in unilateral hearing loss.

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