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Effect of α-lipoic acid on spatial memory and structural integrity of developing hippocampal neurons in rats subjected to sodium arsenite exposure.

07:00 EST 7th January 2020 | BioPortfolio

Summary of "Effect of α-lipoic acid on spatial memory and structural integrity of developing hippocampal neurons in rats subjected to sodium arsenite exposure."

Exposure to arsenic has been reported to affect the nervous system in a number of ways. Various epidemiological studies suggest cognitive impairment in subjects following exposure to environmental arsenic. The goal of the present study was to determine if supplementation of exogenous α-lipoic acid (ALA) could ameliorate sodium arsenite (NaAsO) induced adverse effects on learning and memory and synaptic connectivity in rat hippocampus.

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This article was published in the following journal.

Name: Environmental toxicology and pharmacology
ISSN: 1872-7077
Pages: 103323

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Medical and Biotech [MESH] Definitions

Memory related to spatial information.

Methods used to take into account and incorporate spatial autocorrelation and regional variation into regression analysis models of data that has spatial dependency, and also to provide information on the spatial relationships among the variables.

Measures of spatial cognition and memory.

A 106 amino acid (12 kDa) trefoil factor that contains two trefoil domains and associates with MUCIN-6. It is expressed in the GASTROINTESTINAL TRACT by cells of BRUNNER GLANDS; PYLORIC GLANDS and mucous neck cells. It inhibits GASTROINTESTINAL MOTILITY and GASTRIC ACID secretion and may help maintain the structural integrity of gastric mucus.

Type of declarative memory, consisting of personal memory in contrast to general knowledge.

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