Crustacean Neuroparsins- A Mini-Review.

07:00 EST 11th January 2020 | BioPortfolio

Summary of "Crustacean Neuroparsins- A Mini-Review."

Crustacean neuroparsins are poly-cysteine rich neuropeptides that share some similarities with the ovary ecdysteroidogenesis hormone (OEH) of mosquitoes, the N-terminal end of the growth factor binding protein region of the vertebrate and mollusk insulin-like growth factor binding protein and single insulin binding domain protein. Neuroparsins can promote reproduction and neurite outgrowth in various insects. Though many studies have been made in insects, the amount of work reported in crustaceans is still limited. This review emphasizes the neuroparsins found in decapod crustaceans with references to the neuroparsin first discovered in insects. To be more complete in identifying all the neuroparsin members and to understand the structure/function relationship within a single species, we have collected all neuroparsins from the GenBank and our transcriptome datasets. Then, we employed a comparative approach to study the sequence homology, tissue expression patterns, making predictions of their function and the evolutionary relationship particularly in decapod crustaceans. Results from alignment and phylogenetic studies indicated that the crustacean neuroparsin consist of unique feature that can be used as criteria for their classification. These features include the presence of 12 cysteine residues in the mature peptide, the strict spacing between these cysteine residues and the size of the mature peptide. Because of the limited data in the expression information, the functions of most neuroparsin are unknown. The review will focus on the site of synthesis, expression, functions, the sequence homology and the evolutionary relationship of this group of neurohormones.


Journal Details

This article was published in the following journal.

Name: Gene
ISSN: 1879-0038
Pages: 144361


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