Maternal Obesity Alters circRNA Expression and the Potential Role of mmu_circRNA_0000660 via Sponging miR_693 in Offspring Liver at Weaning Age.

07:00 EST 11th January 2020 | BioPortfolio

Summary of "Maternal Obesity Alters circRNA Expression and the Potential Role of mmu_circRNA_0000660 via Sponging miR_693 in Offspring Liver at Weaning Age."

Maternal obesity predispose offspring to metabolic disorders and obesity, but the mechanisms are not fully understood, especially during early life. Circular RNA (circRNA) can regulate the expression of target genes through the regulatory pathways of competing endogenous RNA (ceRNA). We hypothesized that the offspring of obese dams exhibit impaired metabolic health through the dysregulated expression of hepatic circRNA.


Journal Details

This article was published in the following journal.

Name: Gene
ISSN: 1879-0038
Pages: 144354


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