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Association of CYP11B2 Gene Polymorphism with Preeclampsia in North East of Iran (Khorasan province).

07:00 EST 11th January 2020 | BioPortfolio

Summary of "Association of CYP11B2 Gene Polymorphism with Preeclampsia in North East of Iran (Khorasan province)."

Identification the genetic factors in preeclampsia (PE) are useful to increase the current knowledge of the pathophysiology of the disorder. The genetic factors implicated for all cases of PE remain to be determined. This study was aimed to investigate association between ADD1 1378G>T, AGTR2 1675G>A, AGTR1 1166A>C, NOS3 894 G>T and CYP11B2 -344C>T gene polymorphisms in Iranian women with PE.

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This article was published in the following journal.

Name: Gene
ISSN: 1879-0038
Pages: 144358

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Medical and Biotech [MESH] Definitions

A mitochondrial cytochrome P450 enzyme that catalyzes the 18-hydroxylation of steroids in the presence of molecular oxygen and NADPH-specific flavoprotein. This enzyme, encoded by CYP11B2 gene, is important in the conversion of CORTICOSTERONE to 18-hydroxycorticosterone and the subsequent conversion to ALDOSTERONE.

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