KLF5 Governs Stemness in the Adult Intestinal Stem Cell Niche.

07:00 EST 11th January 2020 | BioPortfolio

Summary of "KLF5 Governs Stemness in the Adult Intestinal Stem Cell Niche."

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Name: Cellular and molecular gastroenterology and hepatology
ISSN: 2352-345X


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Medical and Biotech [MESH] Definitions

A particular zone of tissue composed of a specialized microenvironment where stem cells are retained in a undifferentiated, self-renewable state.

Progenitor stem cells found in the testicles.

Methods of implanting a CELL NUCLEUS from a donor cell into an enucleated acceptor cell. Often the nucleus of a somatic cell is transferred into a recipient OVUM or stem cell (STEM CELLS) with the nucleus removed. This technology may provide means to generate autologous diploid pluripotent cell for therapeutic cloning, and a model for studying NUCLEAR REPROGRAMMING in embryonic stem cells. Nuclear transfer was first accomplished with frog eggs (RANA PIPIENS) and reported in 1952.

The release of stem cells from the bone marrow into the peripheral blood circulation for the purpose of leukapheresis, prior to stem cell transplantation. Hematopoietic growth factors or chemotherapeutic agents often are used to stimulate the mobilization.

Cells from adult organisms that have been reprogrammed into a pluripotential state similar to that of EMBRYONIC STEM CELLS.

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