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308-nm Excimer Laser: a Hopeful and Optional Therapy for Pityriasis Versicolor.

07:00 EST 14th January 2020 | BioPortfolio

Summary of "308-nm Excimer Laser: a Hopeful and Optional Therapy for Pityriasis Versicolor."

Pityriasis Versicolor (PV) is known as a superficial fungal infection. It is suggested that resistant strains to azoles may be developed and hence, the treatment would be difficult. This study aimed to evaluate the efficacy of excimer laser (308 nm) as an alternative therapy for PV. This is a prospective intra-patient left-to-right, randomized, placebo-controlled study conducted on 26 patients with bilateral lesions which are not responding to the PV standard treatment. Patients were randomly assigned to right or left-side therapy for a duration of 8 weeks with either excimer laser (308 nm three times weekly) or topical placebo. Clinical assessment and mycological evaluation were performed before the initiation of treatment and at the 4 and 8 week of therapy. A decrease in the mean clinical score of cases was recorded from 7.1 at the baseline evaluation to 1.56 after 4 weeks and to 1.96 after 8 weeks of treatment. At week 4, there was a statistically significant reduction in the clinical scores compared with pre-treatment scores and with the placebo group (p < .001). 308-nm excimer laser can be considered as a hopeful and optional therapy for PV.

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This article was published in the following journal.

Name: The Journal of dermatological treatment
ISSN: 1471-1753
Pages: 1-19

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