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Can the Durability of Pulmonary Vein Isolation be Predicted by the Time-to-Isolation in Second-generation Cryoballoon Ablation? Insight from the Results of Repeat Procedures.

07:00 EST 14th January 2020 | BioPortfolio

Summary of "Can the Durability of Pulmonary Vein Isolation be Predicted by the Time-to-Isolation in Second-generation Cryoballoon Ablation? Insight from the Results of Repeat Procedures."

Second-generation cryoballoons (2-CBs) are widely used in atrial fibrillation (AF) ablation, however, the optimal freeze dose is still under debate. Recently, the time-to-isolation (TTI), which is the time until an acute pulmonary vein isolation (PVI), is noted based on clinical and experimental studies, and a TTI-guided strategy has been proposed. However, in real-world human CB procedures, the direct association between the TTI and PVI durability has not been well examined. We sought to investigate whether the TTI plus >120 second freezes, when the TTI is <60 seconds, accurately predicts a durable 2-CB ablation PVI.

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Name: Circulation. Arrhythmia and electrophysiology
ISSN: 1941-3084
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Medical and Biotech [MESH] Definitions

The segregation of patients with communicable or other diseases for a specified time. Isolation may be strict, in which movement and social contacts are limited; modified, where an effort to control specified aspects of care is made in order to prevent cross infection; or reverse, where the patient is secluded in a controlled or germ-free environment in order to protect him or her from cross infection.

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