Schwarzinicines A-G, 1,4-Diarylbutanoid-Phenethylamine Conjugates from the Leaves of .

07:00 EST 14th January 2020 | BioPortfolio

Summary of "Schwarzinicines A-G, 1,4-Diarylbutanoid-Phenethylamine Conjugates from the Leaves of ."

Schwarzinicines A-G (-), representing the first examples of 1,4-diarylbutanoid-phenethylamine conjugates, were isolated from the leaves of . The structures of these compounds were determined by detailed analysis of their MS, 1D and 2D NMR data. Compounds - exhibited pronounced vasorelaxant effects in the rat isolated aorta ( 106-120%; EC 0.96-2.10 μM). However, compounds and showed no cytotoxic effects against A549, MCF-7, and HCT 116 human cancer cells (IC > 10 μM).


Journal Details

This article was published in the following journal.

Name: Journal of natural products
ISSN: 1520-6025


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Medical and Biotech [MESH] Definitions

A derivative of phenethylamine containing two substituent methoxy groups in the phenyl ring.

Immunologic techniques based on the use of: (1) enzyme-antibody conjugates; (2) enzyme-antigen conjugates; (3) antienzyme antibody followed by its homologous enzyme; or (4) enzyme-antienzyme complexes. These are used histologically for visualizing or labeling tissue specimens.

The burning of a small, thimble sized, smoldering plug of dried leaves on the SKIN at an ACUPUNCTURE point. Usually the plugs contain leaves of MUGWORT or moxa.

A plant family of the order ZINGIBERALES, subclass Zingiberidae, class Liliopsida best known for banana (MUSA). The slender false trunk, formed by leaf sheaths of the spirally arranged leaves, may rise to 15 meters (50 feet). There is a crown of large leaves at the top.

The custard-apple plant family of the order Magnoliales, subclass Magnoliidae, class Magnoliopsida. Some members provide large pulpy fruits and commercial timber. Leaves and wood are often fragrant. Leaves are simple, with smooth margins, and alternately arranged in two rows along the stems.

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