Topics

Precision medicine and gut dysbiosis.

07:00 EST 14th January 2020 | BioPortfolio

Summary of "Precision medicine and gut dysbiosis."

Infection (CDI) is a leading cause of healthcare-associated infections in Canada, affecting the gastrointestinal tract which can lead to fever, abdominal pain, and diarrhea. Effective treatment for patients with Recurrent CDI (rCDI) can be achieved by Fecal Microbiota Transplantation (FMT) by introducing the gut micro-organisms of a healthy person (donor) into the bowel of the affected individual. Research has shown that an increase in the specific bacterial phyla post-FMT may be partly responsible for this gut restoration and elimination of disease. Furthermore, in understanding the key bacteria associated with successful FMT, full treatment plans can be developed for the individual needs of the patient by matching an infected individual with a donor possessing ideal microbiota for the specific patient. This development of precision medicine and more systematic adoption of FMT can be the next step toward more rapid resolution of rCDI.

Affiliation

Journal Details

This article was published in the following journal.

Name: Healthcare management forum
ISSN: 0840-4704
Pages: 840470419899426

Links

DeepDyve research library

PubMed Articles [12150 Associated PubMed Articles listed on BioPortfolio]

Obstructive Sleep Apnea and Systemic Hypertension: Gut Dysbiosis as the Mediator?

Obstructive sleep apnea (OSA) and systemic hypertension (SH) are common and interrelated diseases. It is estimated that approximately 75% of treatment-resistant hypertension cases have an underlying O...

Qualifying and quantifying the precision medicine rhetoric.

With the rise of precision medicine efforts worldwide, our study objective was to describe and map the emerging precision medicine landscape. A Google search was conducted between June 19, 2017 to Jul...

Impact of Precision Medicine on Efficiencies of Novel Drug Development in Cancer.

Precision medicine offers opportunities for reducing the costs, burdens, and time associated with drug development. We examined time, number of trials, indications tested and patient burden needed to ...

Molecular screening programs in different countries: what we learned and perspectives.

Precision medicine arised as a new paradigm in oncology in which molecular profiling aims at guiding therapy in oncology. The implementation of precision medicine necessitates setting up molecular tum...

The Future of Precision Medicine.

Precision medicine is an emerging framework to maximize therapeutic benefit by modifying the treatment for individual patients based on their variations in demographic, genomic, and environmental fact...

Clinical Trials [2292 Associated Clinical Trials listed on BioPortfolio]

Survey on Precision Medicine and Digital Health

The investigators would like to create an online survey that queries current topics in precision medicine.

DCM Precision Medicine Study

The study aim of the DCM Precision Medicine Study is to test the hypothesis that DCM has a substantial genetic basis and to evaluate the effectiveness of a family communication interventio...

The Comparative Effectiveness Dementia & Alzheimer's Registry

To evaluate the effectiveness of using clinical precision medicine to develop lifecourse interventions for Alzheimer's disease (AD) prevention and treatment. Anthropometrics, blood biomark...

Optimizing Immunosuppression Drug Dosing Via Phenotypic Precision Medicine

Clinical trial applying Phenotypic Precision Medicine (PPM) to tacrolimus dosing in liver and/or kidney transplant recipients to show improvement in maintaining drug trough levels within t...

Implementing Precision Medicine Approaches to Guide Anti-platelet Selection

The study aims to determine the feasibility and clinical utility of incorporating precision medicine approaches, incorporating both cytochrome P450 2C19 (CYP2C19) genotyping and platelet r...

Medical and Biotech [MESH] Definitions

Clinical, therapeutic and diagnostic approaches to optimal disease management based on individual variations in a patient's genetic profile.

Metal devices for fastening together two or more parts of dental prostheses for stabilizing or retaining them by attachment to abutment teeth. For a precision attachment for a partial denture DENTURE PRECISION ATTACHMENT is available.

The detection of genetic variability (e.g., PHARMACOGENOMIC VARIANTS) relevant to PHARMACOGENETICS and PRECISION MEDICINE. The purpose of such genetic testing is to help determine the most effective treatment options and their optimum dosages with least potential risks for DRUG-RELATED SIDE EFFECTS AND ADVERSE REACTIONS.

A precision device used for attaching a fixed or removable partial denture to the crown of an abutment tooth or a restoration. One type is the intracoronal attachment and the other type is the extracoronal attachment. It consists of a female portion within the coronal portion of the crown of an abutment and a fitted male portion attached to the denture proper. (Jablonski, Dictionary of Dentistry, 1992, p85; from Boucher's Clinical Dental Terminology, 4th ed, p264)

Changes in quantitative and qualitative composition of MICROBIOTA. The changes may lead to altered host microbial interaction or homeostatic imbalance that can contribute to a disease state often with inflammation.

Quick Search


DeepDyve research library

Relevant Topics

Infectious-diseases
Antiretroviral Therapy Clostridium Difficile Ebola HIV & AIDS Infectious Diseases Influenza Malaria Measles Sepsis Swine Flu Tropical Medicine Tuberculosis Infectious diseases are caused by pathogenic...

Clostridium difficile (CDI)
A clostridium difficile infection (CDI) is a type of bacterial infection that can affect the digestive system. It most commonly affects people who are staying in hospital.  The symptoms of CDI can range from mild to severe and include: diarrhoe...

Healthcare
Health care (or healthcare) is the diagnosis, treatment, and prevention of disease, illness, injury, and other physical and mental impairments in humans. Health care is delivered by practitioners in medicine, chiropractic, dentistry, nursing, pharmacy, a...


Searches Linking to this Article