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Peanut allergy diagnosis: moving from basic to more elegant testing.

07:00 EST 16th January 2020 | BioPortfolio

Summary of "Peanut allergy diagnosis: moving from basic to more elegant testing."

Peanut allergy (PNA) is an IgE-mediated immune disorder which merits particular attention due to its impact on the health and quality of life of millions of patients worldwide. PNA tends to develop in early life and resolves in only 20% of peanut-allergic children. It accounts for the majority of severe food-related allergic reactions. An accurate diagnosis of PNA is vital. In this review we present the approach to the diagnosis of peanut allergy, starting from the history and proceeding to measures of overall sensitization and then to component-resolved diagnostics and oral food challenges as indicated. Additional testing in development include basophil activation testing and determination of epitopes for peanut allergic responses. Based on the literature stepwise approaches and predictive models for diagnosing PNA are also presented.

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This article was published in the following journal.

Name: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology
ISSN: 1399-3038
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