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Modification of the surface of titanium into titania (TiO2) nanotube (TNT) arrays was performed by electrochemical anodization to design endoprosthesis for maxillofacial surgery. TNT arrays with different surface structures were successfully coated on titanium substrates by varying the anodizing voltages and annealed at 450 °C for 4 h. Phase composition and morphology of the nanotubes were examined by X-ray powder diffraction and field-emission scanning electron microscopy, respectively. Biological functions and water wettability of various surface structures were also investigated. The results demonstrated that the annealed nanotubes were composed of anatase phase only at all applied voltages. Tube diameters and lengths increased as the voltage increased. The surfaces with modification had more wettability, cell adhesion, and proliferation, ALP activity, and calcium deposition than the surfaces without modification. Finally, the results demonstrated that a modified surface of titanium to produce TNT arrays as a biomaterial is promising to design osseointegrated surface of endoprosthesis for maxillofacial surgery.
This article was published in the following journal.
Name: Biomedical materials (Bristol, England)
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