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GPR119 Agonism Revisited: A Novel Target for Increasing β-Cell Mass?

07:00 EST 1st February 2020 | BioPortfolio

Summary of "GPR119 Agonism Revisited: A Novel Target for Increasing β-Cell Mass?"

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Name: Endocrinology
ISSN: 1945-7170
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Medical and Biotech [MESH] Definitions

The phenomenon of antibody-mediated target cell destruction by non-sensitized effector cells. The identity of the target cell varies, but it must possess surface IMMUNOGLOBULIN G whose Fc portion is intact. The effector cell is a "killer" cell possessing Fc receptors. It may be a lymphocyte lacking conventional B- or T-cell markers, or a monocyte, macrophage, or polynuclear leukocyte, depending on the identity of the target cell. The reaction is complement-independent.

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