Blunted circulating irisin in adults with type I diabetes during aerobic exercise in a hot environment: a pilot study.

07:00 EST 13th February 2020 | BioPortfolio

Summary of "Blunted circulating irisin in adults with type I diabetes during aerobic exercise in a hot environment: a pilot study."

Irisin is a novel myokine associated with increased metabolism, which may be upregulated in type 1 diabetes (T1D) during exercise-heat stress. We therefore assessed serum irisin production in young adults with and without T1D during incremental exercise in dry-heat (35°C). The change in irisin during exercise was lower in individuals with compared to without T1D (-1.79 [S.E.M. 25.68] vs. 59.74 [S.E.M. 79.63] pg/mL; p=0.024), indicating that irisin expression during exercise-heat stress is blunted in T1D. Novelty: • We show that, when assessed in young adults with and without T1D during exercise-heat stress, serum irisin production is blunted in T1D.


Journal Details

This article was published in the following journal.

Name: Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme
ISSN: 1715-5320


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