Characterization of a mouse model to study the relationship between apical periodontitis and atherosclerosis.

07:00 EST 13th February 2020 | BioPortfolio

Summary of "Characterization of a mouse model to study the relationship between apical periodontitis and atherosclerosis."

First, to determine the feasibility of using the low density lipoprotein receptor knockout (LDLR KO) mouse model to study apical periodontitis (AP). Second, to investigate the causal relationship between AP and atherosclerosis. It was hypothesized that it would be feasible to induce AP and atherosclerosis in LDLR KO mice and find a difference in atherosclerosis between AP and Sham groups.


Journal Details

This article was published in the following journal.

Name: International endodontic journal
ISSN: 1365-2591


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