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Revisiting the Link Between PGD and BOS in Lung Transplantation: Highlighting the Role of Tregs.

07:00 EST 13th February 2020 | BioPortfolio

Summary of "Revisiting the Link Between PGD and BOS in Lung Transplantation: Highlighting the Role of Tregs."

Regulatory T cells (Tregs) were originally identified as immune cells critical for the maintenance of self-tolerance and prevention of autoimmune disease. However, since their discovery in 1995, Tregs have been found to have an expanded role as master-regulatory cells with simultaneous multi-directional functions in immune tolerance involving both innate and adaptive immunity [1]. Similarly, approaches to predict outcomes after lung transplantation through the translation of emerging knowledge of complex immune network continues to evolve.

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This article was published in the following journal.

Name: Transplant international : official journal of the European Society for Organ Transplantation
ISSN: 1432-2277
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Medical and Biotech [MESH] Definitions

Preparative treatment of transplant recipient with various conditioning regimens including radiation, immune sera, chemotherapy, and/or immunosuppressive agents, prior to transplantation. Transplantation conditioning is very common before bone marrow transplantation.

The transference of either one or both of the lungs from one human or animal to another.

Transfer of HEMATOPOIETIC STEM CELLS from BONE MARROW or BLOOD between individuals within the same species (TRANSPLANTATION, HOMOLOGOUS) or transfer within the same individual (TRANSPLANTATION, AUTOLOGOUS). Hematopoietic stem cell transplantation has been used as an alternative to BONE MARROW TRANSPLANTATION in the treatment of a variety of neoplasms.

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