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ZIAQ: A quantile regression method for differential expression analysis of single-cell RNA-seq data.

07:00 EST 13th February 2020 | BioPortfolio

Summary of "ZIAQ: A quantile regression method for differential expression analysis of single-cell RNA-seq data."

Single-cell RNA sequencing (scRNA-seq) has enabled the simultaneous transcriptomic profiling of individual cells under different biological conditions. scRNA-seq data have two unique challenges that can affect the sensitivity and specificity of single-cell differential expression analysis: a large proportion of expressed genes with zero or low read counts ("dropout" events) and multimodal data distributions.

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Name: Bioinformatics (Oxford, England)
ISSN: 1367-4811
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