Evaluation of the pharmacokinetics and food intake effect of generic sofosbuvir in healthy Chinese subjects

07:00 EST 12th February 2020 | BioPortfolio

Summary of "Evaluation of the pharmacokinetics and food intake effect of generic sofosbuvir in healthy Chinese subjects

Sofosbuvir is an NS5B nucleotide inhibitor that was approved for hepatitis C treatment. Generic sofosbuvir has been produced to improve the affordability. The present study investigated the pharmacokinetics (PK) and safety of generic sofosbuvir as well as the effect of food intake on its PK parameters in healthy Chinese subjects.


Journal Details

This article was published in the following journal.

Name: International journal of clinical pharmacology and therapeutics
ISSN: 0946-1965


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Medical and Biotech [MESH] Definitions

By adjusting the quantity and quality of food intake to improve health status of an individual. This term does not include the methods of food intake (NUTRITIONAL SUPPORT).

Governmental guidelines and objectives pertaining to public food supply and nutrition including recommendations for healthy diet and changes in food habits to ensure healthy diet.

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Measurement and evaluation of the components of substances to be taken as FOOD.

Establishment of the level of a quantifiable effect indicative of a biologic process. The evaluation is frequently to detect the degree of toxic or therapeutic effect.

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