Disrupted Time-Dependent and Functional Connectivity Brain Network in Alzheimer's Disease: A Resting-State fMRI Study Based on Visibility Graph.

07:00 EST 12th February 2020 | BioPortfolio

Summary of "Disrupted Time-Dependent and Functional Connectivity Brain Network in Alzheimer's Disease: A Resting-State fMRI Study Based on Visibility Graph."

Alzheimer's disease (AD) is a progressive neurodegenerative disease with insidious onset, which is difficult to be reversed and cured. Therefore, discovering more precise biological information from neuroimaging biomarkers is crucial for accurate and automatic detection of AD.


Journal Details

This article was published in the following journal.

Name: Current Alzheimer research
ISSN: 1875-5828


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A progressive form of dementia characterized by the global loss of language abilities and initial preservation of other cognitive functions. Fluent and nonfluent subtypes have been described. Eventually a pattern of global cognitive dysfunction, similar to ALZHEIMER DISEASE, emerges. Pathologically, there are no Alzheimer or PICK DISEASE like changes, however, spongiform changes of cortical layers II and III are present in the TEMPORAL LOBE and FRONTAL LOBE. (From Brain 1998 Jan;121(Pt 1):115-26)

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