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Are Biologics Safe in the Immediate Postoperative Period? A Single Center Evaluation of Consecutive Crohn's Surgical Patients.

07:00 EST 4th March 2020 | BioPortfolio

Summary of "Are Biologics Safe in the Immediate Postoperative Period? A Single Center Evaluation of Consecutive Crohn's Surgical Patients."

There is no study to date examining the safety of initiating or restarting biologic therapy following major abdominal surgery for Crohn's disease.

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This article was published in the following journal.

Name: Diseases of the colon and rectum
ISSN: 1530-0358
Pages:

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Medical and Biotech [MESH] Definitions

The period following a surgical operation.

Any process by which toxicity, metabolism, absorption, elimination, preferred route of administration, safe dosage range, etc., for a drug or group of drugs is determined through clinical assessment in humans or veterinary animals.

Pain during the period after surgery.

Strategies required by the US Food and Drug Administration (FDA) Amendments Act of 2007 when a question exists as to whether the benefits of a drug outweigh its risks. These constitute a safety plan with several potential components, including a medication guide, a communication plan, elements to ensure safe use and an implementation system to help guide the prescribers, pharmacists and patients.

A nonsteroidal anti-inflammatory agent with potent analgesic and antiarthritic properties. It has been shown to be effective in the treatment of OSTEOARTHRITIS; RHEUMATOID ARTHRITIS; ankylosing SPONDYLITIS; and in the alleviation of postoperative pain (PAIN, POSTOPERATIVE).

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Relevant Topics

Biotherapeutics
The field encompassing therapeutic materials produced using biological means, including recombinant DNA technology. Biotherapeutics, also known as biotech drugs or biologics, are therapies derived from living organisms. By harnessing these living cells...

Crohn's Disease (CD)
Crohn’s disease (CD) is a long-term condition that causes inflammation of the lining of the digestive system.  Inflammation can affect any part of the digestive system, from the mouth to the back passage, but most commonly occurs in the last s...

Surgical treatments
Surgery is a technology consisting of a physical intervention on tissues. All forms of surgery are considered invasive procedures; so-called "noninvasive surgery" usually refers to an excision that does not penetrate the structure being exci...


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