Extragenital lichen sclerosus successfully treated by topical maxacalcitol/betamethasone butyrate propionate.

08:00 EDT 10th March 2020 | BioPortfolio

Summary of "Extragenital lichen sclerosus successfully treated by topical maxacalcitol/betamethasone butyrate propionate."

Lichen sclerosus (LS) is a benign chronic inflammatory skin disorder affecting the anogenital and extragenital areas, and an autoimmune disease characterized by autoreactive T cells. Clinically and histopathologically, LS and scleroderma are similar. Patients are usually asymptomatic or may present with slightly itchy, white papules with progressive development of parchment-like skin. Topical corticosteroids are recommended as first-line treatment; most patients are initially treated with potent topical corticosteroids.


Journal Details

This article was published in the following journal.

Name: Clinical and experimental dermatology
ISSN: 1365-2230


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Medical and Biotech [MESH] Definitions

Atrophy and shriveling of the SKIN of the VULVA that is characterized by the whitish LICHEN SCLEROSUS appearance, inflammation, and PRURITUS.

A chronic inflammatory mucocutaneous disease usually affecting the female genitalia (VULVAR LICHEN SCLEROSUS) and BALANITIS XEROTICA OBLITERANS in males. It is also called white spot disease and Csillag's disease.

The 17-valerate derivative of BETAMETHASONE. It has substantial topical anti-inflammatory activity and relatively low systemic anti-inflammatory activity.

The 17-valerate derivative of BETAMETHASONE. It has substantial topical anti-inflammatory activity and relatively low systemic anti-inflammatory activity.

A glucocorticoid given orally, parenterally, by local injection, by inhalation, or applied topically in the management of various disorders in which corticosteroids are indicated. Its lack of mineralocorticoid properties makes betamethasone particularly suitable for treating cerebral edema and congenital adrenal hyperplasia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p724)

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