Enhanced Stability of Peptide Nanofibers Coated with a Conformal Layer of Polydopamine.

08:00 EDT 10th March 2020 | BioPortfolio

Summary of "Enhanced Stability of Peptide Nanofibers Coated with a Conformal Layer of Polydopamine."

The susceptibility of self-assembled materials to changes in environmental conditions and mechanical forces often limits their utility for many applications. In this work, the surface of nanofibers formed by  β -sheet peptide self-assembly were coated by polydopamine (PDA) deposition. This conformal coating process rendered the nanofiber dimensions and internal  p -stacking chirality impervious to changes in pH, temperature and physical processing by spin-coating onto a silicon wafer. Whereas, sonication-induced shearing of the DA/NDI-KK composite irreversibly shortened the nanofibers into 100-200 nm segments, the uncoated nanofibers unravelled into single strands upon similar treatment. Additionally, the PDA coated nanofibers could be wrapped by an additional layer comprised of a positively, charged polyelectrolyte polymer.


Journal Details

This article was published in the following journal.

Name: Chemistry (Weinheim an der Bergstrasse, Germany)
ISSN: 1521-3765


DeepDyve research library

PubMed Articles [13729 Associated PubMed Articles listed on BioPortfolio]

Effect of chitosan coating on the properties of nanoliposomes loaded with flaxseed-peptide fractions: Stability during spray-drying.

In this study, production of peptide fractions with different molecular weights (10, 30, and 100 KDa) from flaxseed hydrolysates was investigated. The peptide-fraction with lowest MW (10 KDa) showed t...

Biocompatibility of a polymer-coated membrane possessing a hydrophilic blood-contacting layer: Adsorption-related assessment.

Currently, the foreign surfaces of extracorporeal circulation devices are coated with an acrylate-based copolymer that creates a hydrophilic blood-contacting layer to enhance biocompatibility. Several...

Enhanced stability of piezoelectric nanogenerator based on GaN/V2O5 core-shell NWs with capacitive contact.

Enhanced stability of a piezoelectric nanogenerator (PNG) was demonstrated using c- and m-axis GaN/V2O5 core-shell nanowires (NWs) by analyzing the capacitive coupling of the PNG's output. The NW arra...

Tunable Color Coating of E-Textiles by Atomic Layer Deposition of Multilayer TiO2/Al2O3 Films.

In this study, we successfully fabricated color-coated electronic fibers by depositing Al2O3/TiO2 on commercially available electronic fibers and evaluated their mechanical properties, such as tensile...

Effect of increased pressure on the coated layer profile of steamed rice.

In this study, rice was cooked using high pressure steam (HPS) via the absorption method to form the coated layer. The relationship between the adhesiveness of HPS-cooked rice and the composition of l...

Clinical Trials [4616 Associated Clinical Trials listed on BioPortfolio]

Antimicrobial Effect of Modified Antibiotic Nanofibers for Regenerative Endodontics Procedures

The treatment for immature teeth with pulp necrosis can be carried out through apexification or regenerative endodontics procedures including platelet rich plasma (PRP), platelet rich fibr...

Randomized Study Comparing Two Established Gastrointestinal Suture Techniques - One-layer-continuous Versus Double-layer-continuous Suture

The purpose of this study is to examine the frequency of postoperative complications depending on the number of suture layers in colo-colonic and ileo-colonic anastomoses Hypothesis: doubl...

Effect of Smear Layer on Endodontic Outcome

This study evaluated the effect of removal of smear layer on the success of primary root canal treatment.Patients requiring primary root canal treatment in mature mandibular first and seco...

Evaluation Conformal Radiotherapy for Gynecologic Cancer

The purpose of this study is comparision conformal radiotherapy for gynecologic cancer

Treatment of Coronary In-Stent Restenosis by a Sirolimus (Rapamycin) Coated Balloon or a Paclitaxel Coated Balloon

The aim of the study is to investigate the non-inferiority of the new sirolimus-coated balloon catheters in comparison to the paclitaxel-coated SQP with regard to acute tolerance, safety a...

Medical and Biotech [MESH] Definitions

CONFORMAL RADIOTHERAPY that combines several intensity-modulated beams to provide improved dose homogeneity and highly conformal dose distributions.

DNA analogs containing neutral amide backbone linkages composed of aminoethyl glycine units instead of the usual phosphodiester linkage of deoxyribose groups. Peptide nucleic acids have high biological stability and higher affinity for complementary DNA or RNA sequences than analogous DNA oligomers.

Specialized regions of the cell membrane composed of pits coated with a bristle covering made of the protein CLATHRIN. These pits are the entry route for macromolecules bound by cell surface receptors. The pits are then internalized into the cytoplasm to form the COATED VESICLES.

The external, nonvascular layer of the skin. It is made up, from within outward, of five layers of EPITHELIUM: (1) basal layer (stratum basale epidermidis); (2) spinous layer (stratum spinosum epidermidis); (3) granular layer (stratum granulosum epidermidis); (4) clear layer (stratum lucidum epidermidis); and (5) horny layer (stratum corneum epidermidis).

TRANSPORT VESICLES formed when cell-membrane coated pits (COATED PITS, CELL-MEMBRANE) invaginate and pinch off. The outer surface of these vesicles is covered with a lattice-like network of COP (coat protein complex) proteins, either COPI or COPII. COPI coated vesicles transport backwards from the cisternae of the GOLGI APPARATUS to the rough endoplasmic reticulum (ENDOPLASMIC RETICULUM, ROUGH), while COPII coated vesicles transport forward from the rough endoplasmic reticulum to the Golgi apparatus.

Quick Search

DeepDyve research library

Searches Linking to this Article