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Worldwide, cigarette smoking is a major cause of premature mortality and diseases that can be prevented. Given that people continue smoking despite the health risks, delivering nicotine without combustion should be considered a valuable and much less harmful way to reduce public health burden caused by smoking. E-cigarettes could play such a role if they are proved to be less harmful than combustible cigarettes. Although the number of clinical trials and human studies assessing safety of e-cigarettes is limited, numerous in vitro and in vivo studies reported the potential harmful effects of aerosol generated from e-cigarettes. This article reviews results of major clinical trials and laboratory studies with regard to cancer, cardiovascular and respiratory risk of e-cigarettes. Additionally, it also discusses the potential application of e-cigarettes as smoking cessation tools. Most studies so far indicated that e-cigarettes are less harmful, but this applies only to smokers who completely switched to e-cigarettes. In the opinion of the authors, good quality research is important to establish the tolerance, safety, efficacy, and harm reduction potential of new technologies. Considering a significant role that physicians and other health providers play in helping smokers, there is an urgent need for evidence-based guidelines and recommendations for clinical practitioners on potential benefits and risks of e-cigarette use.
This article was published in the following journal.
Name: Polish archives of internal medicine
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The branch of pharmacology that deals directly with the effectiveness and safety of drugs in humans.
The health status of the family as a unit including the impact of the health of one member of the family on the family as a unit and on individual family members; also, the impact of family organization or disorganization on the health status of its members.
Electronic devices that are designed to provide NICOTINE in the form of an inhaled aerosol. They typically are made in the shape of CIGARETTES in order to simulate the experience of CIGARETTE SMOKING.
A branch of applied ethics that studies the value implications of practices and developments in life sciences, medicine, and health care.
Committees established by professional societies, health facilities, or other institutions to consider decisions that have bioethical implications. The role of these committees may include consultation, education, mediation, and/or review of policies and practices. Committees that consider the ethical dimensions of patient care are ETHICS COMMITTEES, CLINICAL; committees established to protect the welfare of research subjects are ETHICS COMMITTEES, RESEARCH.
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