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Detection of ergosterol by liquid chromatography/electrospray mass spectrometry - investigation of unusual in source reactions.

08:00 EDT 10th March 2020 | BioPortfolio

Summary of "Detection of ergosterol by liquid chromatography/electrospray mass spectrometry - investigation of unusual in source reactions."

In the field of natural products, dereplication of complex mixtures hasbecomes usual practice to annotate known compounds and avoid their re-isolation. To this purpose, many groups rely on liquid chromatography coupled to high resolution mass spectrometry to deduce molecular formulae of compounds allowing comparison with public or in-house databases. Electrospray ionisation is usually considered as the method of choice to investigate a large panel of compounds but, in some cases, it may lead to unusual results as described in the following article for ergosterol.

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This article was published in the following journal.

Name: Rapid communications in mass spectrometry : RCM
ISSN: 1097-0231
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