Over all variability of mitral annular plane peak systolic velocity and peak global longitudinal strain rate in relation to age, body size, and sex: The HUNT Study.

08:00 EDT 10th March 2020 | BioPortfolio

Summary of "Over all variability of mitral annular plane peak systolic velocity and peak global longitudinal strain rate in relation to age, body size, and sex: The HUNT Study."

Left ventricular (LV) systolic global function can be assessed by peak annular systolic velocity S'. Global longitudinal strain rate (GLSR) is relative LV shortening rate, equivalent to normalizing S' for LV length (S' ). It has previously been shown that mitral annular plane systolic excursion (MAPSE) and global longitudinal strain (GLS) have similar biological variability, but GLS normalizes for one dimension only, inducing a systematic error, increasing body size dependence. The objective of this study was to compare S' with GLSR in the same way, comparing biological variability and body size dependence.


Journal Details

This article was published in the following journal.

Name: Echocardiography (Mount Kisco, N.Y.)
ISSN: 1540-8175


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Medical and Biotech [MESH] Definitions

Abnormal protrusion or billowing of one or both of the leaflets of MITRAL VALVE into the LEFT ATRIUM during SYSTOLE. This allows the backflow of blood into left atrium leading to MITRAL VALVE INSUFFICIENCY; SYSTOLIC MURMURS; or CARDIAC ARRHYTHMIA.

Heart murmurs which are systolic in timing. They occur between the first and the second HEART SOUNDS, between the closure of MITRAL VALVE and TRICUSPID VALVE and the closure of semilunar aortic and pulmonary valves. Systolic murmurs include ejection murmurs and regurgitant murmurs.

Backflow of blood from the LEFT VENTRICLE into the LEFT ATRIUM due to imperfect closure of the MITRAL VALVE. This can lead to mitral valve regurgitation.

Measurement of the index of refraction (the ratio of the velocity of light or other radiation in the first of two media to its velocity in the second as it passes from one into the other).

Narrowing of the passage through the MITRAL VALVE due to FIBROSIS, and CALCINOSIS in the leaflets and chordal areas. This elevates the left atrial pressure which, in turn, raises pulmonary venous and capillary pressure leading to bouts of DYSPNEA and TACHYCARDIA during physical exertion. RHEUMATIC FEVER is its primary cause.

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