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Sorafenib is a multikinase inhibitor used to treat advanced hepatocellular carcinoma (HCC). Recently, a preclinical trial has shown that response to sorafenib is associated with a metabolic shift towa...
Corrigendum to Letter regarding Salma et al. "Vital signs changes during different dental procedures: A prospective longitudinal crossover clinical trial" Oral Surg Oral Med Oral Pathol Oral Radiol 128 (2019): 96.
Diagnostic and risk stratification are limited in emergencies. The measurement of microcirculation might identify patients with poor perfusion but compensated macrocirculation such as in beginning sho...
Miridesap, a depleter of serum amyloid P component (SAP), forms an essential component of a novel approach to remove systemic amyloid deposits; low oral bioavailability necessitates that it is given p...
Objective and importance of study: The importance of social determinants for individual health recovery outcomes is well recognised in public health. However, no succinct social health screening (SHS)...
Phase IIa, open clinical trial, pilot, single arm and proof of concept.
The effectiveness of current checklists is hampered by lack of acceptance and compliance. Recently, a new type of checklist with dynamic properties has been created to provide more specifi...
This is a randomised, placebo controlled, double blind, crossover proof of concept study to investigate the efficacy and safety of oral LAT8881 in acute migraine, with or without aura.
The primary purpose of this open-label, Phase 2 proof of concept study is to evaluate the efficacy of 12 months of oral ACH-0144471 in participants with C3G or IC-MPGN based on renal biops...
Proof of concept, double-blind Randomized Controlled Trial with d-Methadone proposed for the first time for use in the treatment of patients diagnosed with primary, moderate to very severe...
An empirical investigation which pertains to the development of prototypes or models that demonstrate the feasibility of novel concepts, ideas, principles, schema or their practical application.
Injections introduced directly into localized lesions.
Injections into the lymph nodes or the lymphatic system.
Injections made into a vein for therapeutic or experimental purposes.
Injections into the cerebral ventricles.