Launching APOLLO: The Role of Genetic Variants in Live- and Deceased-Donor Kidney Transplantation.

07:00 EST 27th December 2019 | BioPortfolio

Summary of "Launching APOLLO: The Role of Genetic Variants in Live- and Deceased-Donor Kidney Transplantation."

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Journal Details

This article was published in the following journal.

Name: Kidney international reports
ISSN: 2468-0249
Pages: 252-254


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Medical and Biotech [MESH] Definitions

Works consisting of speeches or writings in praise of a person or thing, especially a set oration in honor of a deceased person. They differ from FUNERAL SERMONS which are delivered at ceremonies for the deceased prior to their burial or cremation. (From Random House Unabridged Dictionary, 2d ed)

Naturally occurring genetic variations associated with drug response (e.g., dosage, extent and rate of metabolic processes). While these variants are not markers for GENETIC PREDISPOSITION TO DISEASE they influence PHARMACOKINETICS and pharmacodynamics and often occur on genes encoding drug metabolism enzymes and transporters (e.g., ANGIOTENSIN CONVERTING ENZYME; CYTOCHROME P-450 CYP2D6).

One of the first INBRED MOUSE STRAINS to be sequenced. This strain is commonly used as genetic background for transgenic mouse models. Refractory to many tumors, this strain is also preferred model for studying role of genetic variations in development of diseases.

Production of new arrangements of DNA by various mechanisms such as assortment and segregation, CROSSING OVER; GENE CONVERSION; GENETIC TRANSFORMATION; GENETIC CONJUGATION; GENETIC TRANSDUCTION; or mixed infection of viruses.

The physical entity of a deceased human or animal.

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