Visual exploration differences during relational memory encoding in early psychosis.

07:00 EST 6th March 2020 | BioPortfolio

Summary of "Visual exploration differences during relational memory encoding in early psychosis."

Relational memory, or the ability to form contextual associations among items encountered closely in time, is impaired in schizophrenia. The ability to bind items into a relational memory is dependent on the hippocampus, a region that is abnormal in schizophrenia. However, the hippocampus is also involved in exploratory behavior, leaving open the question whether relational memory deficits in schizophrenia are due to failure of relational binding or diminished visual exploration of individual items during encoding. We studied visual exploration patterns during the encoding of face-scene pairs in 66 healthy control subjects and 69 early psychosis patients, to test the hypothesis that differences in visual exploration during the encoding phase can explain task accuracy differences between the two groups. Psychosis patients had lower explicit test accuracy and were less likely to transition from mouth to eyes during encoding. The visual exploration pattern differences between groups did not mediate the relationship between group and explicit test accuracy. We conclude that early psychosis patients have an abnormal pattern of binding items together during encoding that warrants further research.


Journal Details

This article was published in the following journal.

Name: Psychiatry research
ISSN: 1872-7123
Pages: 112910


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Medical and Biotech [MESH] Definitions

Type of declarative memory, consisting of personal memory in contrast to general knowledge.

An area in the temporal lobe that is important for memory encoding and retrieval. It is bordered caudally by the parahippocampal cortex (see HIPPOCAMPUS) and ventrally and medially by the ENTORHINAL CORTEX.

A neuropsychological test designed to assess different memory functions. It may incorporate an optional cognitive exam (Brief Cognitive Status Exam) that helps to assess memory related cognitive function.

A relational pattern in which a person attempts to derive a sense of purpose through relationships with others.

Neurological process involving the conversion of learned information into long-term memory.

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