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Expanded use of reduced complexity approaches in epidemiology and environmental justice investigations motivates detailed evaluation of these modeling approaches. Chemical transport models (CTMs) remain the most complete representation of atmospheric processes but are limited in applications that require large numbers of runs, such as those that evaluate individual impacts from large numbers of sources. This limitation motivates comparisons between modern CTM-derived techniques and intentionally simpler alternatives. We model population-weighted PM source impacts from each of greater than 1100 coal power plants operating in the United States in 2006 and 2011 using three approaches: (1) adjoint PM sensitivities calculated by the GEOS-Chem CTM; (2) a wind field-based Lagrangian model called HyADS; and (3) a simple calculation based on emissions and inverse source-receptor distance. Annual individual power plants' nationwide population-weighted PM source impacts calculated by HyADS and the inverse distance approach have normalized mean errors between 20 and 28% and root mean square error ranges between 0.0003 and 0.0005 µg m compared with adjoint sensitivities. Reduced complexity approaches are most similar to the GEOS-Chem adjoint sensitivities nearby and downwind of sources, with degrading performance farther from and upwind of sources particularly when wind fields are not accounted for.
This article was published in the following journal.
Name: Journal of exposure science & environmental epidemiology
N-of-1 trials allow inference between two treatments given to a single individual. Most often, clinical investigators analyze an individual's N-of-1 trial data with usual t-tests or simple nonparametr...
The very term 'running-related overuse injury' implies the importance of 'use', or exposure, to running. Risk factors for running-related injury can be better understood when exposure to running is qu...
This paper deals with classification of dose distributions of nuclear workers based on antikurtosis (Q) and entropy coefficient (K) and their relationship presented in QK-diagrams. It is shown that di...
Developing methods to efficiently analyze 3D point cloud data of plant architectures remains challenging for many phenotyping applications. Here, we describe a tool that tackles four core phenotyping ...
The incorporation of evidence derived from multiple research designs into one single synthesis can enhance the utility of systematic reviews making them more worthwhile, useful and insightful. Methodo...
Consecutive patients with long-standing complex regional pain syndrome II in a lower limb are treated with graded exposure therapy in vivo in combination with methods targeting cortical re...
This study evaluates the feasibility of endo-laparoscopic full-thickness resection with simple suturing technique which did not expose gastric mucosa to peritoneum (simple non-exposure EFT...
The current study sought to translate laboratory research on learning and memory to better understand the mechanisms and methods for implementing exposure therapy for unwanted obsessional ...
Melamine and phthalates are environmental emerging chemicals, which are ubiquitously present in the public and easily contacted by children through air, foods, and skin. This study aims to...
This study compares three established, manual based psychotherapies for Complex Post-traumatic Stress disorder (CPTSD) in patients with childhood trauma (e.g. sexual abuse, violence). The ...
Seizures that occur during a febrile episode. It is a common condition, affecting 2-5% of children aged 3 months to five years. An autosomal dominant pattern of inheritance has been identified in some families. The majority are simple febrile seizures (generally defined as generalized onset, single seizures with a duration of less than 30 minutes). Complex febrile seizures are characterized by focal onset, duration greater than 30 minutes, and/or more than one seizure in a 24 hour period. The likelihood of developing epilepsy (i.e., a nonfebrile seizure disorder) following simple febrile seizures is low. Complex febrile seizures are associated with a moderately increased incidence of epilepsy. (From Menkes, Textbook of Child Neurology, 5th ed, p784)
The specific failure of a normally responsive individual to make an immune response to a known antigen. It results from previous contact with the antigen by an immunologically immature individual (fetus or neonate) or by an adult exposed to extreme high-dose or low-dose antigen, or by exposure to radiation, antimetabolites, antilymphocytic serum, etc.
The prevention of infection or disease following exposure to a pathogen. This is most frequently addressed by administering a vaccine or anti-viral medication following exposure to a virus.
Methods for assessing flow through a system by injection of a known quantity of an indicator, such as a dye, radionuclide, or chilled liquid, into the system and monitoring its concentration over time at a specific point in the system. (From Dorland, 28th ed)
Improving health status of an individual by adjusting the quantities, qualities, and methods of nutrient intake.