Parahydrogen-Induced Radio Amplification by Stimulated Emission of Radiation.

08:00 EDT 24th March 2020 | BioPortfolio

Summary of "Parahydrogen-Induced Radio Amplification by Stimulated Emission of Radiation."

Radio amplification by stimulated emission of radiation (RASER) was recently discovered in a low-field NMR spectrometer incorporating a highly specialized radio-frequency resonator, where a high degree of proton-spin polarization was achieved by reversible parahydrogen exchange. RASER activity, which results from the coherent coupling between the nuclear spins and the inductive detector, can overcome the limits of frequency resolution in NMR. Here we show that this phenomenon is not limited to low magnetic fields or the use of resonators with high-quality factors. We use a commercial bench-top 1.4 T NMR spectrometer in conjunction with pairwise parahydrogen addition producing proton-hyperpolarized molecules in the Earth's magnetic field (ALTADENA condition) or in a high magnetic field (PASADENA condition) to induce RASER without any radio-frequency excitation pulses. The results demonstrate that RASER activity can be observed on virtually any NMR spectrometer and measures most of the important NMR parameters with high precision.


Journal Details

This article was published in the following journal.

Name: Angewandte Chemie (International ed. in English)
ISSN: 1521-3773


DeepDyve research library

PubMed Articles [14729 Associated PubMed Articles listed on BioPortfolio]

Modulation of Caspase-3 activity using a redox active vitamin K3 analogue, plumbagin, as a novel strategy for radioprotection.

Radiation induced damage to normal cells is a major shortcoming of conventional radiotherapy, which necessitates the development of novel radio-protective drugs. An ideal radio-modulator would protect...

Role of Diosmin in protection against the oxidative stress induced damage by gamma-radiation in Wistar albino rats.

The benchmark of this study is to evaluate the radio protective efficiency of diosmin, a natural citrus flavone of hesperidin derivative on radiation-induced damage in wistar albino rats. Rats orally ...

Blackbody Radiation-Induced Population Transfer Dynamics from Highly Vibrationally Excited Levels of the 0 () Ion-Pair State of I.

We report the decay dynamics from the highly excited vibrational levels of the 0 () ion-pair state of I. Strong UV fluorescence belonging to the 0 () → Σ transition was observed upon the excitati...

Impact of the PrC-210 Radioprotector Molecule on Cancer Deaths in p53-Deficient Mice.

Radiation-induced cancer is an ongoing and significant problem, with sources that include clinics worldwide in which 3.1 billion radiology exams are performed each year, as well as a variety of other ...

Pulse-Programmable Magnetic Field Sweeping of Parahydrogen-Induced Polarization by Side Arm Hydrogenation.

Among the hyperpolarization techniques geared toward in vivo magnetic resonance imaging, parahydrogen-induced polarization (PHIP) shows promise due to its low cost and fast speed of contrast agent pre...

Clinical Trials [10135 Associated Clinical Trials listed on BioPortfolio]

Prevention of Radiotherapy Induced Enteropathy by Probiotics (PREP)

In recent studies, a radiation-induced enteropathy is being reported over 50%. In clinics, probiotics are actively prescribed as a treatment for radiation-induced enteropathy. If probiotic...

Evaluation of the Unstimulated Whole Saliva Flow During and After Radiotherapy, With the Use HcT20

The aim of this report was to evaluate the unstimulated whole saliva flow in patients with head and neck cancers during and after the exclusive radiotherapy with an association of lauryl-d...

Laser CO2 Versus TENS After Reconstruction of the Rotator Cuff

The purpose of this study is to evaluate the most effective method between Transcutaneous Electrical Stimulation and Light Amplification by Stimulated Emission of Radiation therapy carbon ...

Curcumin for the Prevention of Radiation-induced Dermatitis in Breast Cancer Patients

Ionizing radiation is a toxic agent and widely accepted form of treatment for various types of cancer. Despite advances in medical technology, radiation therapy still causes severe early a...

Radiation- Induced Alopecia in Patients Undergoing Radiation Therapy to the Brain

Study will be conducted on patients receiving Whole brain(WB) / Partial Brain(PB) radiotherapy using volumetric modulated arc therapy or intensity modulated radiotherapy at Department of R...

Medical and Biotech [MESH] Definitions

An optical source that emits photons in a coherent beam. Light Amplification by Stimulated Emission of Radiation (LASER) is brought about using devices that transform light of varying frequencies into a single intense, nearly nondivergent beam of monochromatic radiation. Lasers operate in the infrared, visible, ultraviolet, or X-ray regions of the spectrum.

Electromagnetic radiation which does not produce ions in matter through which it passes. Its wavelengths are generally greater than those of far ultraviolet radiation and range through the longest radio waves.

Abnormally high temperature intentionally induced in living things regionally or whole body. It is most often induced by radiation (heat waves, infra-red), ultrasound, or drugs.

Leukemia produced by exposure to IONIZING RADIATION or NON-IONIZING RADIATION.

The use of a radiation monitoring device composed of material which emits light after being illuminated. The amount of light emitted is proportional to the amount of IONIZING RADIATION to which the material has been previously exposed.

Quick Search

DeepDyve research library

Searches Linking to this Article