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Increased Risk of Velopharyngeal Insufficiency in Patients Undergoing Staged Palate Repair.

08:00 EDT 24th March 2020 | BioPortfolio

Summary of "Increased Risk of Velopharyngeal Insufficiency in Patients Undergoing Staged Palate Repair."

To evaluate the association of 2-stage cleft palate (CP) surgery on velopharyngeal insufficiency (VPI) incidence, speech surgeries, and cleft-related surgical burden.

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Journal Details

This article was published in the following journal.

Name: The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
ISSN: 1545-1569
Pages: 1055665620913440

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Medical and Biotech [MESH] Definitions

Failure of the SOFT PALATE to reach the posterior pharyngeal wall to close the opening between the oral and nasal cavities. Incomplete velopharyngeal closure is primarily related to surgeries (ADENOIDECTOMY; CLEFT PALATE) or an incompetent PALATOPHARYNGEAL SPHINCTER. It is characterized by hypernasal speech.

A group of muscles attached to the SOFT PALATE (or velum) and the PHARYNX. They include the superior constrictor, the PALATOPHARYNGEUS, the levator veli palatini muscle, and the muscularis uvulae. This sphincter is situated between the oral and nasal cavities. A competent velopharyngeal sphincter is essential for normal speech and swallowing.

The structure that forms the roof of the mouth. It consists of the anterior hard palate (PALATE, HARD) and the posterior soft palate (PALATE, SOFT).

Tumors or cancer of the PALATE, including those of the hard palate, soft palate and UVULA.

A hematopoietic growth factor which promotes proliferation and maturation of neutrophil granulocytes. Clinically it is effective in decreasing the incidence of febrile neutropenia in patients with non-myeloid malignancies receiving myelosuppressive therapy or in reducing the duration of neutropenia and neutropenia-related clinical sequelae in patients with non-myeloid malignancies undergoing myeloblastive chemotherapy followed by BMT. It has also been used in AIDS patients with CMV retinitis being treated with GANCICLOVIR. (Gelman CR, Rumack BH & Hess AJ (eds): DRUGDEX(R) System. MICROMEDEX, Inc., Englewood, Colorado (Edition expires 11/30/95))

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Relevant Topics

Cleft Palate and Cleft Lip
Cleft means 'split' or 'separation', and in Cleft Palate and Lip, the palate and lip are split respectively. This occurs as a congenital abnormality because during development in the womb, the face develops in sections which fuse together...

Surgical treatments
Surgery is a technology consisting of a physical intervention on tissues. All forms of surgery are considered invasive procedures; so-called "noninvasive surgery" usually refers to an excision that does not penetrate the structure being exci...


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