Initial experience with scalp sparing radiation with concurrent temozolomide and tumor treatment fields (SPARE) for patients with newly diagnosed glioblastoma.

08:00 EDT 23rd March 2020 | BioPortfolio

Summary of "Initial experience with scalp sparing radiation with concurrent temozolomide and tumor treatment fields (SPARE) for patients with newly diagnosed glioblastoma."

Standard of care for glioblastoma includes concurrent chemoradiation and maintenance temozolomide with tumor treatment fields (TTFields). Preclinical studies suggest TTFields and radiation treatment have synergistic effects. We report our initial experience evaluating toxicity and tolerability of scalp-sparing radiation with concurrent TTFields.


Journal Details

This article was published in the following journal.

Name: Journal of neuro-oncology
ISSN: 1573-7373


DeepDyve research library

PubMed Articles [10975 Associated PubMed Articles listed on BioPortfolio]

A Comparison of Radiation Techniques in Patients Treated With Concurrent Chemoradiation for Stage III Non-Small Cell Lung Cancer.

The standard of care in management of patients with good performance status and unresectable stage III non-small cell lung cancer (NSCLC) therapy is concurrent chemoradiation. Newer techniques such as...

Response to 'Folliculitis decalvans-like pustular plaques on the limbs sparing the scalp'.

Oncologic Safety and Outcomes in Patients Undergoing Nipple-Sparing Mastectomy.

Nipple sparing mastectomy (NSM) is an alternative to skin sparing mastectomy in appropriately selected patients. The aim of this study was to review our experience with NSM and to evaluate for oncolog...

Disease-Related Outcomes and Toxicities of Intensity-Modulated Radiation Therapy Following Lung-Sparing Pleurectomy for Malignant Pleural Mesothelioma: A Systematic Review.

To explore the use of intensity-modulated radiotherapy (IMRT) after lung-sparing surgery in malignant pleural mesothelioma (MPM). Because severe toxicities have been documented following radiotherapy ...

Radiation Induced Brain Aneurysms: Institutional Experience and State of Art in the Contemporary Literature.

Brain aneurysms (BA) represent the most common intracranial vascular condition, with an overall incidence of 1-2%. Among the described common causes of their initial formation and growth the role of r...

Clinical Trials [9500 Associated Clinical Trials listed on BioPortfolio]

Concurrent Chemo-Radiation Form NSCLC to a Individualized MLD

Our group has shown in a modeling study that increasing the radiation dose to pre-specified normal tissue dose constrains could lead to increased TCP with the same NTCP in patients with no...

Esophageal Sparing Intensity-modulated Radiation Therapy (IMRT) for Locally-Advanced Thoracic Malignancies

Hypothesis 1- Using IMRT, the RT dose can be safely escalated from 58 Gy to 74 Gy given as 6 fractions/week with concurrent chemotherapy. Hypothesis 2- Esophageal motion can be used to cu...

Safety and Efficacy of a Topical Scalp Treatment for Dry Scalp Conditions in Children and Adult

The purpose of this study is to determine if YoBee, a topical treatment for dry scalp conditions, is safe and effective in clinically improving dry scalp conditions. The investigators will...

Radiation- Induced Alopecia in Patients Undergoing Radiation Therapy to the Brain

Study will be conducted on patients receiving Whole brain(WB) / Partial Brain(PB) radiotherapy using volumetric modulated arc therapy or intensity modulated radiotherapy at Department of R...

Radiation Therapy and Concurrent Cisplatin Chemotherapy for Locally Advanced or Metastatic Malignant Melanoma

The study is a prospective phase II trial of radiation therapy concurrent with cisplatin chemotherapy in the treatment of locally advanced or metastatic melanoma in patients who are deemed...

Medical and Biotech [MESH] Definitions

Skin diseases involving the SCALP.

A general term describing various dermatophytoses. Specific types include TINEA CAPITIS (ringworm of the scalp), TINEA FAVOSA (of scalp and skin), TINEA PEDIS (athlete's foot), and tinea unguium (see ONYCHOMYCOSIS, ringworm of the nails). (Dorland, 27th ed)

A therapeutic approach, involving chemotherapy, radiation therapy, or surgery, after initial regimens have failed to lead to improvement in a patient's condition. Salvage therapy is most often used for neoplastic diseases.

The ability of some cells or tissues to withstand ionizing radiation without serious injury. Tolerance depends on the species, cell type, and physical and chemical variables, including RADIATION-PROTECTIVE AGENTS and RADIATION-SENSITIZING AGENTS.

First segment of axon that connects distal axon segments to the neuronal CELL BODY at the axon hillock region. The axon initial segment is not protected by the MYELIN SHEATH and has properties critical for axonal growth. The axon initial segment and the axon hillock form an axonal trigger zone.

Quick Search

DeepDyve research library

Searches Linking to this Article