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Ischemic stroke and dose adjustment of oral Factor Xa inhibitors in patients with atrial fibrillation.

08:00 EDT 23rd March 2020 | BioPortfolio

Summary of "Ischemic stroke and dose adjustment of oral Factor Xa inhibitors in patients with atrial fibrillation."

Oral Factor Xa inhibitors for the prevention of stroke in atrial fibrillation require dose adjustment based on certain clinical criteria, but the off-label use of the reduced doses is common.

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This article was published in the following journal.

Name: Journal of neurology
ISSN: 1432-1459
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Medical and Biotech [MESH] Definitions

A drug combination of aspirin and dipyridamole that functions as a PLATELET AGGREGATION INHIBITOR, used to prevent THROMBOSIS and STROKE in TRANSIENT ISCHEMIC ATTACK patients.

A morpholine and thiophene derivative that functions as a FACTOR XA INHIBITOR and is used in the treatment and prevention of DEEP-VEIN THROMBOSIS and PULMONARY EMBOLISM. It is also used for the prevention of STROKE and systemic embolization in patients with non-valvular ATRIAL FIBRILLATION, and for the prevention of atherothrombotic events in patients after an ACUTE CORONARY SYNDROME.

The application of repeated, brief periods of vascular occlusion at the onset of REPERFUSION to reduce REPERFUSION INJURY that follows a prolonged ischemic event. The techniques are similar to ISCHEMIC PRECONDITIONING but the time of application is after the ischemic event instead of before.

The dose amount of poisonous or toxic substance or dose of ionizing radiation required to kill 50% of the tested population.

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