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Normalized grip strength is a sensitive outcome measure through all stages of Duchenne muscular dystrophy.

08:00 EDT 21st March 2020 | BioPortfolio

Summary of "Normalized grip strength is a sensitive outcome measure through all stages of Duchenne muscular dystrophy."

The main aim was to explore the changes in hand-grip strength in patients with Duchenne muscular dystrophy (DMD) aged 5-29 years. Secondary aims were to test the effect of mutation, ambulatory status and glucocorticoid use on grip strength and its changes over time and to compute the number of subjects needed for a clinical trial to stabilize grip strength.

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This article was published in the following journal.

Name: Journal of neurology
ISSN: 1432-1459
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Medical and Biotech [MESH] Definitions

A measure of the binding strength between antibody and a simple hapten or antigen determinant. It depends on the closeness of stereochemical fit between antibody combining sites and antigen determinants, on the size of the area of contact between them, and on the distribution of charged and hydrophobic groups. It includes the concept of "avidity," which refers to the strength of the antigen-antibody bond after formation of reversible complexes.

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