Mechanistic investigation of photochemical reactions by mass spectrometry.

08:00 EDT 24th March 2020 | BioPortfolio

Summary of "Mechanistic investigation of photochemical reactions by mass spectrometry."

This Minireview highlights applications of ESI-MS (ElectroSpray Ionization Mass Spectrometry) for investigations of photochemical reactions. We show possible approaches to on-line ESI-MS monitoring of photocatalytic reactions and give examples of characterization of short-lived photochemical intermediates by ion spectroscopy. The minireview also exemplifies in-depth mass spectrometric studies of photoisomerization reactions and photofragmentation reactions. Apart from mechanistic studies, the coupling of photochemistry and mass spectrometry is a powerful approach in studying structure and properties of biomolecules. We show several examples focused on investigation of intrinsic properties of model biomolecules.


Journal Details

This article was published in the following journal.

Name: Chembiochem : a European journal of chemical biology
ISSN: 1439-7633


DeepDyve research library

PubMed Articles [13261 Associated PubMed Articles listed on BioPortfolio]

Mechanistic understanding of catalysis by combining mass spectrometry and computation.

Mechanistic studies are of great importance for the understanding, optimization, and design of chemical reactions, especially catalysis. In recent years, the combination of mass spectrometry and compu...

A Mechanistic Study of Protonated Aniline to Protonated Phenol Substitution Considering Tautomerization by Ion Mobility Mass Spectrometry and Tandem Mass Spectrometry.

We report the use of ion mobility mass spectrometry (IMMS) and energy-resolved collisional activation to investigate gas-phase reactions of protonated aniline and protonated phenol. Protonated aniline...

Detection of ergosterol by liquid chromatography/electrospray mass spectrometry - investigation of unusual in source reactions.

In the field of natural products, dereplication of complex mixtures hasbecomes usual practice to annotate known compounds and avoid their re-isolation. To this purpose, many groups rely on liquid chro...

Characterizing chain-end structures formed during initiation reactions of radical polymerization for MMA-St-BA terpolymer using pyrolysis-gas chromatography-atmospheric pressure chemical ionization-high resolution time-of-flight mass spectrometry.

Analyzing polymer end groups using pyrolysis (Py) gas chromatography-mass spectrometry (GC/MS) in multi-component polymer samples is not an easy task because of the insufficient sensitivity, selectivi...

Mechanistic Study of Thermal Decomposition of Hexamethyldisilaneby Flash Pyrolysis Vacuum Ultraviolet Photoionization Time-of-Flight Mass Spectrometry and Density Functional Theory.

Thermal decomposition of hexamethyldisilane (HMDS) was studied from room temperature to 1310 K using flash pyrolysis vacuum ultraviolet single-photon ionization time-of-flight mass spectrometry (VUV-S...

Clinical Trials [4923 Associated Clinical Trials listed on BioPortfolio]

Extending Urine Analysis By Direct Mass Spectrometry

We aim to evaluate the effect of an extension of conventional urine diagnostics with mass spectrometry in patients with a suspected UTI. Mass spectrometry is done directly from the urine s...

Time to Appropriate Antibiotic Between Using Microarray Assay and Mass Spectrometry Technique

This is an experimental study of participants who had positive blood culture to compare time to appropriate antibiotic between using Microarray Assay and Mass Spectrometry to bacterial Ide...

Amyloidosis Typing Using Mass Spectrometry-based Proteomics: a New Accurate Tool for Difficult Typing

The main objective is to establish that a new technique of amyloidosis typing by Proteomics (based on nanoLC-MS/MS mass spectrometry) allows typing in > 90% of observations in patients who...

Mass Spectrometry in Single Bladder Cancer Cells

The study is a pilot study in the feasibility of a diagnostic technique. There is no current data on detection of cisplatin in cancer cells derived from human urine. This study will genera...

Biomarker Screening of PCOS With IR by Metabonomics Technique and Its Relationship With TCM Syndrome Type

The type-2 diabetes mellitus(T2DM), metabolic syndrome, cardiovascular disease complications induced by polycystic ovary syndrome(PCOS) with insulin resistance(IR), which become serious ...

Medical and Biotech [MESH] Definitions

A mass spectrometry technique using two (MS/MS) or more mass analyzers. With two in tandem, the precursor ions are mass-selected by a first mass analyzer, and focused into a collision region where they are then fragmented into product ions which are then characterized by a second mass analyzer. A variety of techniques are used to separate the compounds, ionize them, and introduce them to the first mass analyzer. For example, for in GC-MS/MS, GAS CHROMATOGRAPHY-MASS SPECTROMETRY is involved in separating relatively small compounds by GAS CHROMATOGRAPHY prior to injecting them into an ionization chamber for the mass selection.

A microanalytical technique combining mass spectrometry and gas chromatography for the qualitative as well as quantitative determinations of compounds.

An analytical method used in determining the identity of a chemical based on its mass using mass analyzers/mass spectrometers.

A mass spectrometry technique used for analysis of nonvolatile compounds such as proteins and macromolecules. The technique involves preparing electrically charged droplets from analyte molecules dissolved in solvent. The electrically charged droplets enter a vacuum chamber where the solvent is evaporated. Evaporation of solvent reduces the droplet size, thereby increasing the coulombic repulsion within the droplet. As the charged droplets get smaller, the excess charge within them causes them to disintegrate and release analyte molecules. The volatilized analyte molecules are then analyzed by mass spectrometry.

Chemical reactions effected by light.

Quick Search

DeepDyve research library

Relevant Topic

Multiple Sclerosis MS
Multiple sclerosis (MS) is the most common disabling neurological condition affecting 100,000 young adults in the UK. The condition results from autoimmune damage to myelin, causing interference in nerve signaling. Symptoms experienced depend on the pa...

Searches Linking to this Article