Topics

Recent progresses in analytical GC and LC mass spectrometric based-methods for the detection of emerging chlorinated and brominated contaminants and their transformation products in aquatic environment.

08:00 EDT 13th March 2020 | BioPortfolio

Summary of "Recent progresses in analytical GC and LC mass spectrometric based-methods for the detection of emerging chlorinated and brominated contaminants and their transformation products in aquatic environment."

This paper is an overview of screening methods recently developed for emerging halogenated contaminants and their transformation products. The target screening methods are available only for a limited number of emerging pollutants since the reference standards for these compounds are not always available, but a risk assessment of those micropollutants in environment must be performed anyhow. Therefore, the chromatographic techniques hyphenated with high resolution mass spectrometry (HRMS) trend to become indispensable methods for suspect and non-target screening of emerging halogenated contaminants. HRMS is also an effective tool for tentatively identification of the micropollutants' transformation products existing in much lower concentrations. To assess the transformation pathway of halogenated contaminants in environment, the non-target screening methods must be combined with biodegradation lab experiments and also with advanced oxidation and reduction processes that can mimic the transformation on these contaminants in environment. It is expected that in the future, the accurate-mass full-spectra of transformation products recorded by HRMS will be the basic information needed to elucidate the transformation pathways of emerging halogenated contaminants in aquatic environment.

Affiliation

Journal Details

This article was published in the following journal.

Name: The Science of the total environment
ISSN: 1879-1026
Pages: 137914

Links

DeepDyve research library

PubMed Articles [35855 Associated PubMed Articles listed on BioPortfolio]

Challenges and applications of isotachophoresis coupled to mass spectrometry - a review.

Electrophoretic separations are of growing interest to tackle complex analytical challenges. Nevertheless, capillary electrophoresis, as the most common mode, still suffers from insufficient detection...

Detection of 5α-reductase inhibitors by UPLC-MS/MS: Application to the definition of the excretion profile of dutasteride in urine.

An analytical procedure based on ultra-performance liquid chromatography-mass spectrometry was developed to screen and to confirm dutasteride and its metabolites in human urine. Sample preparation inc...

Visual detection for nucleic acid-based techniques as potential on-site detection methods. A review.

Nucleic acid-based techniques could achieve highly sensitive detection by amplifying template molecules to millions of folds. It has been one of the most valued analytical methods and is applied in ma...

Mass spectral fragmentation of perfluoroacyl derivatives of half nitrogen mustards for their detection by Gas Chromatography - Mass Spectrometry.

Analytical methods for the detection and identification of half nitrogen mustards (halfNMs), i.e., partial hydrolyzed product of nitrogen mustards (pHpNMs), using silyl derivatives are often associate...

Recent advances in breath analysis to track human health by new enrichment technologies.

Detection of biomarkers in exhaled breath has been gaining increasing attention as a tool for diagnosis of specific diseases. However, rapid and accurate quantification of biomarkers associated with s...

Clinical Trials [12204 Associated Clinical Trials listed on BioPortfolio]

CD71 in Dried Blood Spots in Healthy Males

Understand the effect of recombinant EPO (rEPO) boosting and microdosing on the hematological module of the Athlete Biological Passport (ABP) - Measure the change in CD71 longitudinall...

MS Detection of Somatic Mutations in Hematological Malignancies

Detection of somatic mutations in hematological malignancies is now routinely assessed by NGS sequencing. This powerful approach is nevertheless time consuming and its costs represent limi...

iKnife REIMS Project

There are currently no widely accepted methods which provide real time in vivo, in situ tissue diagnostics within the operating theatre environment. This project proposes that the oncolog...

The Effect of n-3 PUFA-riched Plant Oil Intake on Human Metabolism

The findings of previous experiments suggested that polyunsaturated fatty acids(PUFAs) has been linked to anti-hyperlipidemia, and reducing the risk of cardiovascular disease.This is a ran...

CLUSTER Trial for Outbreak Detection and Response

Despite the critical importance of identifying hospital-associated outbreaks as early as possible in order to limit their spread, there are currently no standardized methods for cluster de...

Medical and Biotech [MESH] Definitions

An analytical method used in determining the identity of a chemical based on its mass using mass analyzers/mass spectrometers.

Methods utilizing the principles of MICROFLUIDICS for sample handling, reagent mixing, and separation and detection of specific components in fluids.

A mass spectrometric technique that is used for the analysis of a wide range of biomolecules, such as glycoalkaloids, glycoproteins, polysaccharides, and peptides. Positive and negative fast atom bombardment spectra are recorded on a mass spectrometer fitted with an atom gun with xenon as the customary beam. The mass spectra obtained contain molecular weight recognition as well as sequence information.

A class of natural contraceptive methods in which SEXUAL ABSTINENCE is practiced a few days before and after the estimated day of ovulation, during the fertile phase. Methods for determining the fertile period or OVULATION DETECTION are based on various physiological indicators, such as circulating hormones, changes in cervical mucus (CERVIX MUCUS), and the basal body temperature.

A mass-spectrometric technique that is used for microscopic chemical analysis. A beam of primary ions with an energy of 5-20 kiloelectronvolts (keV) bombards a small spot on the surface of the sample under ultra-high vacuum conditions. Positive and negative secondary ions sputtered from the surface are analyzed in a mass spectrometer in regards to their mass-to-charge ratio. Digital imaging can be generated from the secondary ion beams and their intensity can be measured. Ionic images can be correlated with images from light or other microscopy providing useful tools in the study of molecular and drug actions.

Quick Search


DeepDyve research library

Searches Linking to this Article