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Tricellular junctions.

08:00 EDT 23rd March 2020 | BioPortfolio

Summary of "Tricellular junctions."

Bosveld and Bellaïche discuss the composition and assembly of tricellular junctions, as well as their roles in cell packing, tissue mechanics and signalling.

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Journal Details

This article was published in the following journal.

Name: Current biology : CB
ISSN: 1879-0445
Pages: R249-R251

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Medical and Biotech [MESH] Definitions

Connections between cells which allow passage of small molecules and electric current. Gap junctions were first described anatomically as regions of close apposition between cells with a narrow (1-2 nm) gap between cell membranes. The variety in the properties of gap junctions is reflected in the number of CONNEXINS, the family of proteins which form the junctions.

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Cell-cell junctions that seal adjacent epithelial cells together, preventing the passage of most dissolved molecules from one side of the epithelial sheet to the other. (Alberts et al., Molecular Biology of the Cell, 2nd ed, p22)

A group of homologous proteins which form the intermembrane channels of GAP JUNCTIONS. The connexins are the products of an identified gene family which has both highly conserved and highly divergent regions. The variety contributes to the wide range of functional properties of gap junctions.

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